CRISPR Meets Nutrigenomics: A Complementary Strategy for Gene Regulation in Atherosclerosis
- Beschreibung
Nutrition plays a fundamental role in maintaining human health, as nutrients profoundly influence gene expression and overall physiological function. In this narrative review, we first examine the molecular pathophysiology of atherosclerosis, highlighting how nutritional factors modulate gene regulation. We then explore how CRISPR technology can be utilized to precisely regulate genes involved in metabolic disorders, offering potential strategies for the prevention and control of atherosclerosis. Given that nutritional compounds can affect multiple genetic targets, this review also evaluates evidence from animal and human studies to identify key genes involved in the inflammatory pathways of atherosclerosis. Finally, we discuss how genome-wide CRISPR screening can be applied to identify and manipulate these genes to favor protective outcomes against atherosclerosis.
- Beschreibung des interdisziplinären Teils des Projekts
- In this project, topics such as nutrition, genomics, gene regulation, and atherosclerosis come together to explore how lifestyle and molecular factors interact in health and disease. By reading and analyzing scientific papers, students will learn how to understand research methods, identify important findings, and recognize what questions remain unanswered. This process helps them develop key academic skills such as critical thinking, literature analysis, scientific writing, and idea generation. It also teaches them how to structure and organize a literature review, preparing them to design and communicate their own research projects more effectively.
- Projektzeitraum
- Wintersemester 2025/2026
- Bewerbungszeitraum
- 13. bis 27.10.2025
- Durchführung
- semesterbegleitend
- Studienfach
-
Biotechnologiy
Molekulare Ernährungswissenschaft
Ernährungsmanagement und Diätetik
Ernährungswissenschaft
Food Biotechnology
Food Science and Engineering
Food Science and Technology
Lebensmittelwissenschaft und Biotechnologie
Medizinische Ernährungswissenschaft - Betreuende
- Sepideh Sadighbathi
- Institut
- Institut für Ernährungswissenschaften (140) (Nutrition, Nutritional biochemistry)
- Sprache
- englisch
- Teilnehmendenanzahl
- min. 1, max. 2
- Arbeitsaufwand
-
ca. 30 Stunden pro Teilnehmende:r
| 1
ECTS-Punkte
Arbeitsaufwand (Stunden und ggf. ECTS) sind ungefähre Angaben. Die tatsächlich vergebenen ECTS-Punkte ergeben sich aus der tatsächlich geleisteten Arbeit.
- Für dieses Projekt ist kein Motivationsschreiben des Studierenden erforderlich
- Projektart
- theoretisch/nicht experimentell
- Lernziele
-
Die Teilnehmende lernen in diesem Projekt:
- Understand how nutrition, genes, and atherosclerosis are connected.
- Learn the basic ideas behind nutrigenomics and CRISPR gene editing.
- Practice reading and analyzing scientific papers to find key information.
- Improve their ability to think critically and spot research gaps.
- Build practical skills in scientific writing, literature review, and idea development for future projects.
- Anmerkungen für Studierende
- You will be provided with all the steps and a whole support to learn each steps covering from basics.
- Based on your collaboration, your name could be among the authors. This is good opportunity to showcase your ability of research for your future career.
- Schlagworte
- Gentechnik, Ideenbildung, Micronutrient intake, Molekulargenetik