Investigating melatonin beyond sleep regulation – role in antioxidant capacity in follicular fluid
- Beschreibung
Melatonin, the tryptophan-derived indoleamine, is recognized as a key player in regulating our sleep patterns and circadian rhythms. Recent research has unveiled additional roles, showcasing other benefits, such as anti-aging, immune modulation, cancer prevention, and diabetes regulation. Its potent antioxidant properties have made it a trending topic in recent scientific studies due to its extraordinary ability to combat oxidative stress in various organs, including reproductive tissues.
While melatonin’s presence in reproductive fluids like seminal plasma and follicular fluid has already been described, its relationship with blood circulation and changes during different stages of follicle development remains unclear. This study seeks to shed light on this connection, potentially opening new insights into how melatonin influences fertility and reproductive health.
The project will pursue the establishment of a method to detect melatonin levels and determine a potential correlation in blood and follicular fluid collected from follicles at different developmental stages using high-performance liquid chromatography (HPLC). Involved students will learn basic hands-on training using HPLC to characterize, purify, and quantify compounds.
- Projektzeitraum
- Sommersemester 2025
- Bewerbungszeitraum
- 01. bis 13.04.2025
- Durchführung
- semesterbegleitend
- Details zu Projektzeitraum und Durchführung
By arrangement
- Studienfach
-
Biologie
Ernährungswissenschaft
Lebensmittelchemie - Betreuende
- Dr. Juan Carlos Gutierrez Anez, Alexander Koza
- Institut
- Institut für Ernährungswissenschaften (140) (Fachgebiet für Molekulare Ernährungswissenschaft)
- Sprache
- deutsch/englisch
- Teilnehmendenanzahl
- min. 1, max. 2
- Arbeitsaufwand
-
ca. 150 Stunden pro Teilnehmende:r
| 5
ECTS-Punkte
Arbeitsaufwand (Stunden und ggf. ECTS) sind ungefähre Angaben. Die tatsächlich vergebenen ECTS-Punkte ergeben sich aus der tatsächlich geleisteten Arbeit.
- Für dieses Projekt ist kein Motivationsschreiben des Studierenden erforderlich
- Projektart
- experimentell
- Lernziele
-
Die Teilnehmende lernen in diesem Projekt:
In this project, participants will learn:
- Getting acquainted with a scientific research project
- Acquiring fundamental techniques in analytical chemistry
- To get hands-on HPLC training for compound characterization, purification, and quantification.
- Assessing, interpreting, and presenting scientific data
- Anmerkungen für Studierende
- Schlagworte
- Melatonin, antioxidants, Follicular Fluid, Chromatography, Oxidative Stress